PEP is a course of anti-HIV medication that needs to be taken daily over the course of a month. The drugs have been available for HIV prevention since the early- to mid-1990s for health workers who have had ‘needle-stick’ or similar injuries. More recently, PEP has been made available under strict prescribing guidelines to people who might have been exposed to HIV during sex.

The sooner PEP is started, the more effective it is. So you must act fast if you want PEP; within 24 hours of the risk is best and no later than 72 hours (3 days).

PEP can cause severe side effects such as diarrhoea, nausea and prolonged headaches.
PEP can be available from sexual health clinics and hospital accident and emergency departments. Many men say they have had difficulty obtaining PEP from these places, especially outside metropolitan areas. You are more likely to be successful if you enquire at a sexual health clinic or A&E in a hospital where there is also a specialist HIV clinic.

You must also meet the prescribing guidelines for PEP – to find out if you are likely to meet the criteria, use our online self-assessment tool.

PEP has a good chance of stopping someone getting HIV but it’s not guaranteed to work and it’s not a cure for HIV. Condoms and lube are still the best way of stopping the spread of HIV.

The information included on this site is for educational purposes only. It is not intended nor implied to be a substitute for professional medical advice. The reader should always consult his or her healthcare provider to determine the appropriateness of the information for their own situation or if they have any questions regarding a medical condition or treatment plan. Reading the information on this website does not create a physician-patient relationship.